By the way, this is really trippy... there are 2 T. w's... Anyway, I just wanted to add to the advice that follows, a couple of times when she has made a big mess of her clothes, I have made her wear the same outfit everyday for a week... dirt, spills, and all. I tell her, "If you don't want to take care of all your pretty clothes, you will not get to wear them."
I hate to say, this seems to be the way some little ones are wired. My kids are both complete disaster makers... hopefully the baby doesn't follow in their footsteps (my sister only has one of five like this). I have gotten rid of more than half their toys and books, and a lot of clothes just to make the cleanup less troublesome. I have put a lock on my soon-to-be 4 daughter's closet, which helps a lot since she can't open her closet. If I forget to lock it, I know that I will be the one cleaning up. All her clothes, most of her books and toys are in the closet. I try to put in her dresser just enough clothes for the week (they don't always stay there).
Her closet is a bifold style. There are two kind of locks that work. One is rectangular and slides over the bifold part of each door (can be purchased at home depot). That one didn't fit in the space between the bifold door and the area above it. So I bought a swinging latch that is about 2" long and swings down over a small metal plate which had to be attached to the closet door. It works very well, and I have to reach above the closet to open and close it. My children did get it open once with a stool and a broomstick. I gave them a talking to and they have not done it again (besides, I think it's too much trouble). I hope this helps, good luck! : )