L.M.
You are sweet to help yourfriend like this. I am constantly reading about inflammatory conditions. I came across this a while back and found it interesting. It discussed hormone allergy as a possible cause if IC.
http://www.onlineallergycenter.com/treatments/interstitia...
This is another link on that site which discuss hormone allergy in more detail:
http://www.onlineallergycenter.com/treatments/hormone_imb...
She may want to consider finding out which foods cause inflammation for her as well. Many people have had good results this way. Gluten (found in weat, barley and rye), dairy and soy are allergenic for some people and could be the culprits.
I wish your friend a helathy pregnancy.
~L.