Nope, I wouldn't do it. I didn't even get the AFP blood test during my pregnancy that tells you if you could possibly have markers for genetic diseases. This is the blood test you usually get BEFORE even thinking about getting an amnio. If you get the AFP test done and it comes back positive, then maybe you should think about getting an amnio done. However, that test very often has false positives. So, you might want to follow that up by a Level II ultrasound done by a perinatologist. They can look for other markers in the babies brain, heart, spinal cord, etc. This is a MUCH less invasive way to look for possible defects, with no risk of miscarriage or other complications.
The question I asked myself was:
If you get the amnio, and it turns out something is wrong.. would you terminate the pregnancy?
My answer was no, absolutely not. If something was wrong, we would deal with it. There was absolutely no way, I'd be able to go through the whole pregnancy knowing something might be wrong and not being able to do anything about it. So, I chose not to know. The risks of the amnio are way too high, so why do it and put my baby at risk, when chances are she was perfectly fine?
I don't know... it's a very personal decision, one that only you and your partner can make. I would highly suggest that you talk to your doctor about the procedure and the risks involved, also do some research on your own so you can make an educated decision.