J.P.
I recently looked into several daycares and preschools for my one and a half year-old daughter. I decided on Kindercare, because the staff was wonderful and the kids had plenty of creative activities to do throughout the day. It is corporate, but the perks include lots of supervision, stable, structured days, and high standards for safety and cleanliness. The cost was about average for similar places. For us, at three full days a week, the total was about $650 a month.
The one I went to is on SE 22nd and Gladstone, but there are several in the Portland area. You can go to kindercare.com to find out more about them. Good luck! I hope you find something that works best for your family.