Do you smoke or drink alcohol regularly? These are proven wrinkle makers. Most people who do either or both will eventually get mouth wrinkles and weathered skin in general.
While a few have a genetic predisposition for this (look at grandma, aunts, mom, and sis for a preview) there are supplements you can take that are scientifically proven to slow down the aging process... particularly with the skin.
Read up on something called Co-Q10 and it's close cousin Ubiquinol. Most vitamin shops sell this supplement. There are many articles on it's benefits.
Check both the Dr. Oz website and Dr. Mercola www.mercola.com
PS: Just because certain cosmetics are dermatologist approved doesn't mean they're good for us. The truth is most anti-aging products and lotions are terrible for our skin and can actually speed the aging process because they jave a lot of dangerous chemicals that actually break down the skin layers and can actually permanently damage it. Both sites I recommend also have alot of information on this as well, and I believe the Mercola site has alot on this. They also pedal so-called safe cosemetics in the store.