YEP! There are a couple different kinds:
From genetically altered http://www.allerca.com/ that has actually been tested on people who are severely allergic/ asthma triggering and has no effect on them (super pricey at apx 6k per cat) aka actually NON-allergenic
to one of the 7 breeds that their DNA altered at random sometime in the past to produce fewer of the proteins/ dander to be HYPO-allergenic. Of ALL of the ones below, most of the allergic-to-all-cats-but-this-one people I know have the Siberian (at the bottom of the list). You would want to spend some time with any of these breeds to see how sensitive your allergy is:
(cut and paste)
Balinese: Often referred to as the "long-haired Siamese," the Balinese looks like an unlikely candidate for a hypoallergenic cat. But it is one of the few breeds that produces less of the Fel D1 protein than other cats, thus causing fewer allergic reactions in allergy sufferers.
Oriental Shorthair: They're hypoallergenic, but it's still a good practice to groom your cat frequently (brushing as well as wiping her down) to keep dander to a minimum.
Javanese: Like the Balinese, the Javanese sports a medium-long single coat that doesn't mat. Because of the lack of undercoat, they have less fur which translates into fewer allergens.
Two "Rex" cats are on the list: the Devon and Cornish Rex. Both shed very little fur, which is good news for allergy sufferers:
Devon Rex: Of the two, the Devon has both shorter fur and less fur. Your Devon Rex will need to have her paw pads and ears cleaned of oil build-up frequently, but doesn't need frequent full baths like the Sphynx or Cornish Rex.
Cornish Rex: The Cornish Rex requires more upkeep than the Devon because they require frequent baths to mitigate the oil buildup on their skin.
The last two cats on the list offer you a choice of hairless or hairy:
Sphynx: The hairless Sphynx is the cat most often associated with being hypoallergenic. Being hairless does not mean they're maintenance-free, however. Your Sphynx will need frequent baths to remove the gummy buildup of oils on her skin, and her large ears will also require frequent cleanings.
Siberian: Like the Balinese, the Siberian sports a moderately long coat, but still is hypoallergenic due to the lower-than-average enzyme levels in their saliva. Some claim that 75 percent of cat allergy sufferers have no reaction to the Siberian.