The first time I left my son for 10 days, my mum watched him.
Why am I bringing this up?
Because my dad took 2 weeks off work so he could be there, too.
If your parents are involved grandparents, and you trust them, don't EXPECT them to take time off work, but sakes alive, give them the option! :) :) :) They may not want to take vacation time to watch their grandchild, or they may be thrilled to.
You have several months to start working this.
One thing I did, was to have my parents watch my son overnight 1 day a month.
He's 9 now. Occasionally we miss months (health, travel, etc.), but he's spent the night once a month with my mum for most of his life. Nana & Papa sleepovers are sacred things. He goes over to their house, because their own home is situated for them / easiest for them to be in... but I know many families who do things in reverse when it's travel time (people come to their house).
Nothing ventured, nothing gained.