D.B.
I'd go with "ay ay ay" because of the repetition. But I think "ay-yi-yi" is the way most Americans say it, emphasizing the "y" as a consonant - I'm guessing it entered the lexicon after Ricky Ricardo kept saying it to Lucy!
"Aye aye aye" would mean "yes yes yes" as in "Aye aye, Sir."
And yeah, "oy vey" is just as useful. Lots of Yiddish expressions and words are better than most anything else: shlep, chutzpah, schmuck, etc. Sometimes it's better if you don't really know the real meaning in Yiddish, by the way! You wouldn't use some of them otherwise.