J.H.
I wouldn't think that a spoon full of honey would cause that much of a problem. There is probably as much sugar in a serving of juice. I would say give him a dose of Tylenol or Motrin at bedtime. If his throat hurts, that will help with the pain and possible swelling so he will be able to sleep better. I'm sure you are already forcing fluids as well. That will help with any secretions he is having. He may also be having allergy issues. We are still covered in pollen over here in Alabama. If his nose is running clear instead of yellow, I might think of calling his doc to see if he can have a dose of Zyrtec at night.
Hope you all rest better soon!