Help? - Tinley Park,IL

Hi,
I am very sorry for your losses.
I have a homozygous C677T mutation. I found out after my second preterm labor and placental abruption. My son was stillborn at 22 weeks, and my daughter was 25 weeks when she was born. Sadly, her lungs were just too immature and she died in the NICU after 5 weeks. My first pregnancy was perfect, and my Daughter who is now four was full term. After my diagnosis I went to a perinatologist, who had me take a baby aspirin and a folgard (folate, B6 and B12) along with my PNV. After I concieved, I switched from the aspirin to Innohep (a low molecular weight heparin like lovonox). I switched from the Innohep to regular heparin for the last couple weeks of the pregnancy. This pregnancy was complication free, and my son was born full term. He is now four months and doing great. I am still taking the Folgard, the PNV and aspirin, and will continue those indefinitely.
I am not familiar with Dr. Lederer, but if s/he is a regular OB who can handle high risk pregnancies, then s/he should be willing to handle your care along with a perinatologist co-managing your case. That is how I was treated.
I hope you will have a smooth pregnancy. My prayers are with you.

-Jackie

A close cousin of mine was diagnosed with the same thing and had to take the baby asprin and Lovinax. I know in her case it was a genetic predisposition to the disorder. She really hated giving herself the shots but in the end she had a healthy baby boy. If you have any concerns or questions that didn't get answered I would definetely not hesitate to get a second opinion.

You should ask to have your cortisol checked. HIGH cortisol would cause this. I would ask for the saliva cortisol test.

Low dose folic acid will help reduce homosystiene also.

It is possible that holy basil, zinc, magnesium, and low dose naltrexone could help as well. These are all excellent to take when cortisol is high.

High cortisol will cause the same things your "syndrome' does- diabetes, heart problems, kidney problems. I think it might be your real root cause. Getting cortisol tested, and under control if need be.... is key.

Usually high cortisol goes along with low potassium so potassium foods are good also- potato, banana, etc.....

low dose folic acid helps your syndrome as well.

Regardless how great the doc is, I would see a specialist just in the off-chance of a mis-diagnosis.

Be well, and all the best.

Dr. Lederer did my IVF transfer which gave me my beautiful baby girl.

That assessment sounds about right. I took baby aspirin and lovenox when I was pregnant with my daughter. Dr. Lederer was not my primary RE but did my transfer. Dr. Coulam put me on the Lovenox and baby aspirin. You will have to be switched over to heparin toward the end of your pregnancy.