J.S.
When I traveled for work (2 weeks out of every month on average), I rolled.
I rolled dress shirts, dress slacks, and all the other casual clothes. Dress shirts should be hung in the shower at the hotel for about 10-15 with the shower running full on hot. Everything else comes out ready to wear!
I did this at least 100-200 times - still do when I pack my own suitcase - but Mrs. is convinced she packs us together better than I can pack my own.
Oh, and yes, less space. It's not a ton of extra space, but in the world of luggage it was enough to matter. My stuff was no longer crushed together, and I had extra room for a pair of shoes (in an airport carryon size upright suitcase)