K.R.
my first guess is teething. if she doesn't settle in a couple minutes, go calm her (pacifier, lovey, holding...) briefly, then put her back down so you don't overstimulate and disrupt the rest of her sleeping patterns. We've also used the numbing cream (just a dot) to rub on the gums/sore area. This just happened to our 15 mo old this month while a huge molar breaks through.