Hi D.,
I went with my brother, his wife, and their ~3 year old son to Florida many years ago. We stayed at my parents' home. My brother and his wife then went for a vacation to the Keys. I stayed with my nephew so he would have someone he knew with him. He always wanted me in sight, even while I was in the bathroom. When they returned, he clung to me. He was in an unfamiliar place with unfamiliar people except for me. He warmed up to them soon after.
Your daughter will be at home with your spouse, I assume. Her routine will be the same, so I think she will be fine while you are gone and when you return. Call her when you are able so that she can hear from you. Can you Skype while you are away? That would be great.
I think all will be fine.
Have a great trip,
: ) Maureen