I would start very slowly, have a long term goal like 18 months or 2 years and start by letting her only have it for the car and bed. make a big deal about it being yucky and spitting it out when she wakes up and putting it up until nap time. If she needs it for car rides make a big deal about putting it up after the ride is over and not getting it back until she is buckled in. There will be some whining, stick to your guns.
Once you have weaned her off of day time use, to just naps and bedtime, work on the idea of giving her pacies to a baby you know, or just babies in general, that she is a big girl and doesn't need them any more.
Ideas, on removing all together...
Place them all in a box and take them to a friend with a baby.
Put them in a box and take them to the post office and "mail" them to The Babies...just attach a note to the box for the mail man to throw away the box after you leave.
Go to Build-a-Bear and build a new friend and stick pacie inside.
Get some helium ballons and send pacie to the clouds.
Whatever way you chose, once you have decided the time has come, do it and get ride of all of them so that you aren't tempted to give them back and she doesn't find one. She will probably whine and cry for about 3 days but that will be it.
My 2 year old cried 15 minutes the first 2 times he had to go to sleep without it and he would say " I need my sussy, please mommy." So sad, so if you can do it before she can really talk, that would be better, IMO.
Good luck, you are doing the right thing.