S.J.
It upset my tummy, but not so bad that I couldn't take it at all. I had to start out very slowly, cutting the pill into literally fifths and taking a little at a time. I could never take an entire pill at once, but that was me. I eventually moved up to taking half a pill at once with a meal. We conceived that way within a few months! Why on earth does your doc want you to eventually be on 2 pills per day so soon? You shouldn't go up to that high of a dose unless one pill a day is not working, I would think. I would really press for some answers with regard to that dosage.
I didn't lose weight with it. But, when I started I was very thin so I didn't have anything to lose.
I recommend your idea of taking it before bedtime. That did help. And ask your doc about starting with half a pill in the beginning to help with stomach upset if you are concerned. There is no reason to rush into taking a full pill at once. Let your body get used to it.
Good luck! I was thrilled with my conception results each time I took this med, and the most I ever took was half a pill per day!
=)