J.C.
Can't give any great tips on the infant, I'd as your Pediatricain for tips, but for the 6 yr old take a child-sized bk pack. Pack it w/ sugarless gum (for chewing if ear problems occur) colors/ coloring book or sticker books, small etch-a sketch, or small travel size magna-doodle toy. If possible, also get some small prize type toys at the dollar store or Target $1 bins, get about 8-10 of them. Put in some travel size wipes, little hand sanitizer, a few nutritious snacks and juice boxes (freeze over night). Pack the food & drink in lrg ziploc bags. I've made my child a "travel only backpack" since she was a toddler and we travel several times/yr. When they get to age 8-11, do new paperbk books, inexpensive handheld elec. travel games like UNO and snacks/drinks (frozen b4) Keep 1/2 the $1 toys for the going trip then switch to the coming home trip. When you get bk home put the back pack away and keep it only for travel. It is almost Christmas each time you bring it out. You can change out a few toys as the child get older inexpensivley. THis works for long car trips too. Don't open the bk pack until you are in the air or on the road a few miles out. My daughter is now a teenager and I quit the travel bk ok at about 12. She still talks about what fun she had with them traveling. Best of luck Mom.