It's your decision to make. But just FYI, I left my oldest son when he was 2, with my in-laws for 11 days when my husband and I went to Australia. My son was fine. We planned/suggested a few things to do to break up the time (i.e. go to an indoor play area, etc), but they really just took care of it all. We made suggestions for things to eat, foods my son liked, etc., and made a general schedule for them. But it all worked out well. He only had maybe 1 or 2 times where they felt he "missed" us...he was usually too busy and occupied with grandma and grandpa to notice. If your daughter is comfortable with them now, she will be when you are gone, too, if you decide to leave her. It's harder on the parents, I think, than the kids!