Hi M. - I feel your pain! I work full-time and am breast-feeding a one year old. Here are some things that helped me get through when I was so sick of pumping:
This may not be an option for you, but co-sleeping was a huge help for me. This meant that baby was doing a bit of reverse-cycling and nursing during the night to make up for milk she didn't get during the day. Rolling over and putting my boob in her mouth wasn't too disruptive to my sleep, or hers. Some nights she was an extremely restless sleeper and those nights stank, but on the whole I think we got more sleep having her in the bed with us. It helps to have a partner who is willing to take baby on the nights when she's really flailing and the boob hasn't helped.
At 8 months, I cut down my pumping sessions at work from 3 to 2. The diminish in my supply was minimal, but the increase in my peace of mind was huge! I also only left baby whatever I'd pumped the day before. I figured that would even out the supply and demand cycle so that she would nurse more heavily in the mornings and evenings when I was home, and it seemed to work just fine. There were days when she was not happy with the amount of milk in the bottle, but other days when she wouldn't drink all that I left her. Overall, she adjusted well to consolidating her feedings to every 4 hours.
On evenings and weekends I let baby nurse on demand.
It would be great if you could elimiate that middle of the night pump session. Even if you don't want to co-sleep, have you considered nursing your boo in the middle of the night instead? Baby will save you the trouble of pumping, and will get all the milk and more that you were going to offer in the course of 24 hours. I know, the thought of risking a wide-awake baby in the middle of the night stinks, but it's a thought. Alternately, like someone else suggested, you can pump first thing in the morning before baby nurses. Baby is a lot better at getting milk out of your boob than the pump. One mama said she had a routine of pumping first thing in the morning, then taking a shower (the warm water helps stimulate milk flow) and then nursing baby before she left for the day. It worked well for her. After a few days, your boobs will know to make more milk at that time of day rather than the middle of the night.
Good luck! Send me a line if you want to chat about this. I am trying to figure out how to proceed with my work pumping, since I plan to continue nursing until baby is 2 or older. We will probably face some of the same issues.
D.