S.S.
If you're asking for depression, I have been taking 5 HTP which boosts serotonin levels in the brain. It seems to be working, even if it's a placebo effect. I don't know about taking homeopathic in addition to prescription, but if you're not taking anything else, I am truly impressed at how much better I am dealing with life. The 5HTP was recommended by several mamas, along with many other choices.
Good luck,
S.