Just read your post on feeling guilty. I would suggest that your issue has nothing or very little to do with your hormones. You are overwhelmed momma. You have so much on your plate and you are trying to be supermom. It doesn't work that way. You are exhausted and stressed and frustrated and even angry (though that may be getting stuffed enough to show up as depression and/or explosions).
It may be time to reevatuate the idea that you need to "do it all right." Doing things right may look completely different from what you are thinking. I would suspect that you think right is doing it all perfectly and all by yourself. How about doing it right is providing your children with the healthiest mom possible instead. A healthy mom cares for herself, she lets go of the unimportant things, she knows when to ask for and accept help, she shows her children how to love themselves by how she loves herself, she puts herself on the top of the list, she becomes realistic rather than idealistic, and she understands that self-care, saying no, and having boundaries is the most important thing ever.
Guilt is a treacherous emotion. It is deceptive. We think that guilt will make us do things right. All guilt does it make us feel really bad and causes us to be sick. Instead of guilt, get curious about what is really truly necessary and let go of the "shoulds." Guilt is not serving you, it is really causing you a lot of chaos. Instead just say: "Yep, I'm not perfect, I'm not able to get it all done, I'm overwhelmed and tired. Okay. So what choices do I have that will support me in feeling better and allowing me to be more available to my little ones?"
Those little ones are going to grow faster than you can imagine. Take the time now to create the best environment for you to be the best you (not the perfect you because that is just crazy making). Because the best you is what your girls need more than a stressed out you striving for perfection.
Be gentle with yourself. Take good care of yourself. Treat yourself to some tender loving care and you will be amazed how much calmer you become both emotionally and physically. A great book is Cheryl Richardson's "The Art of Extreme Self-Care."