D.D.
the "lizards" you speak of are probably geckos. If you get rid of the geckos you will probably be overrun with spiders, and I don't mean the "good kind". So you need to decide which one you would rather have; Spiders (which can bite and cause serious harm) or geckos (which harm no one but the bugs).
However, you CAN keep them out of your house. Go around and make sure all of your windows and doors seal properly. Buy extra find steel wool and place it in all the weep holes around your house foundation. Check and make sure the gasket on the bottom of your garage door is sealing properly.
I hope this helps. :-)