My husband and I go through cars like most people go through clothes. We've had many company cars, many needs to for upgrading, downgrading, etc.
My best advice is to look for the kid of car you like and then how the latch systems in those cars are situated.
In 2008, we both had company cars. Mine was MUCH bigger - 2008 Ford Taurus. His was smaller - 2007 Chevy Impala, but because of how the latches were situated in the car, he was able to get more things in the car between the kids than I could. His latches were closer to the door while mine were more in the interior.
With gas prices rising and minivans/suvs still getting awful gas mileage (we just got a new Honda Pilot that's averaging less than 16 mph), I'd recommend taking all of that into consideration.
My husband currently drives a new Subaru Legacy (sedan), has plenty of room in the backseat for our 2 car seats and gets great gas mileage (~26 mph). Even though I looked like a Granny in my Taurus, I really miss it as an economical, extremely safe vehicle.
I'd also recommend checking out sites like Motortrend, Car & Driver, etc. to see what professional and consumer reviews are there for good family cars.