Hi J.,
First off, congrats to your husband on his promotion! What a wonderful opportunity, especially in this economy.
I am very familiar with the Tampa area. You will LOVE it! So close to some of the best beaches in America. Great activities for children. You'll love the weather in the winter (summer is just like the summer's here - hot and humid).
Yes, we have moved from a different state, back when we first got married and I was pregnant with my first child, 13 years ago. Do what you can to find friends with similar interest - join a church, a mom's group, enroll your kids in activities, etc.
Best wishes to you! It may be a little hard at first, but hang in there and find all those great things to do in Tampa, and soon you'll feel right at home!!
S. :)