M.T.
When my sister turned 50, I made her up a bag of things, everything that I could find that came in packages of 50. I discovered that many, many things came in packages of 48! But she got a bag of funny items - a roll of pennies, a bottle of some kind of vitamins, a package of googlie eyes like for crafts, a package of safety pins, a bunch of other stuff. I supplemented it with my favorite book for birthday girls, "It's My F-ing Birthday" by Merrill Markoe.
I hope your sis enjoys turning fabulous 50!