I'm going to assume that since he's been seen by an endocrinologist, that he's already seen a urologist. So, the urethra is fine, the kidneys and liver are fine, what's next? It's really not all that unusual for a child this age to be "out of touch" with their bodies. I'm not a professional, but I have seen a LOT of kids who were growing at such a rapid rate (bodies in constant transition) that they often couldn't recognize the sensation until it was too late. (My daughter was already over four feet tall in the first grade.) There are pads that you can buy to be placed in the childs underwear that will give an immediate cold sensation when they are touched by wetness, and the company I bought them from gave a money back guarantee (but this was years ago). They look a lot like a maxi pad (thin with an adhesive back), and the kid often forgets that they are wearing one unless they have an accident, then the gel in the pad reacts to the moisture, and it feels like an ice-pack. They also have different styles to accomodate both genders. You could also take a holistic approach. I don't know how much attention you pay to ingredient labels, but maybe take a closer look next time you go to the grocery store. For instance: when the label on the frozen lasagna says "no preservatives," take a closer look, chances are there is a ridiculous amount of sodium in the product. Even things like a loaf of bread often include high levels of high fructose corn syrup (concentrated sugar) and either preservatives or high sodium levels in order to to increase the breads shelf life. High levels of sugar and sodium are horrible for the body, and yet they can be found in most of the products we buy. Sodium makes the body retain fluid, and sugars can wreak havoc all over. It might be worth while to talk to a nutritionist. Also, you could try assisted meditation and yoga. No, I'm not a hippie mom, but those things can really help. My daughter has ADHD, and those were things her counselor suggested to me. It has helped with a number of issues, not the least of which was my child being in tune with her own body. A year ago, the poor kid tripped over her own feet, now she's earning belts and breaking boards in Tae Kwon Do. You don't have to go to an expensive yoga studio, we just bought a mat and a beginners video from Books a Million. I can't promise you that these things will work, as you said, every kid is different, but they might just be worth a try. And don't forget that you are NOT alone!!! The shame, the embarrassment, the helplessness, the frustration, the bills, the steam cleaning for the carpets and furniture, and the never ever ending laundry... A lot of us have been there, now it's our turn to be here for you. Don't lose hope. There is an answer waiting out there somewhere, and as hard as you are working, I'm sure you will find it. Good luck!