From someone who's been in the job market a lot myself...I know how difficult this is! I've been looking for a job since last October, and my top advice is MAKE FOLLOW-UP CALLS! Don't wait for employers to call you. They receive hundreds, sometimes thousands of resumes/applications. Tell your husband to look up the main phone number of a company after he submits an application. Call there and ask for human resources. He'll probably get a general voice mail box...LEAVE A MESSAGE! The first time I did this, I thought it was such a long shot, but it worked! The only responses I received to my applications were places I called myself. Don't be discouraged...he'll probably get calls back from maybe 1 out of 8 or 10 companies he calls. Also, it might take a long time. Sometimes up to a month before they call back.
Other advice:
Continue networking like you're doing here on MamaSource. Everyone you meet, mention you're looking for a job, and be as specific as possible with what type of job. Some employers are put off by people who don't know what they want.
Resources & advice on Monster.com:
Monster.com has a great resource center with a good blog. You can post messages and network with other job hunters. Talking to others in the same situation helps you keep your confidence up, which is hugely important thru this process. There are also sample interview questions, sample letters, etc... I've found Monster.com to be huge and cumbersome with their job postings, and I haven't gotten response from employers when I submit to jobs there. Probably because there are SO many responders from that board. But, their resources really are helpful.
Keep your chin up YOURSELF too. I'm sure you have a lot of stress yourself being the one employed. Try to be as supportive as possible with a positive attitude. My husband has taken this approach with me, it really has empowered me with a better sense of confidence that I can find and keep a job. I'm a big believer that things happen for a reason, and your family will wind up better than before once this process is done!