E.D.
It takes me 15 minutes to assemble, pump, and clean up. I put my pump into the backpack pre assembled. When I take it out at work all I have to do is set out some paper towels to catch the containers and shields when I'm finished. Next I plug in the tubing and then plug the machine into an outlet. I use lanolin cream on my nipples each time I pump. It helps them to not chafe and I think it helps the pump create a better suction. I sort of squeeze my boobs while holding the pump in place, like a boob sandwich, and then pump for 10 minutes. If I need to, I'll use a higher setting to expedite the process. The lanolin helps to make that possible. When I'm finished I just use the breast pump wipes to wipe down the shields and other parts. It's not sterile, but I don't think it needs to be. When I get home I run the pieces through the dishwasher.
Best of luck!
http://www.amazon.com/Quick-Clean-Breastpump-Accessory-Wi...
ETA: I do disassemble the breastshield from the valve (?), and I wipe inside of the membrane.