S.G.
I was on Depo for some time and it was horrible for me. I gained a LOT of weight, and probably had other side effects (this was about 10 years ago). I had to stop using it. I ended up getting on the pill. I was really attracted to it because I always would forget my pill, but it just wasn't for me. Oh, and I didn't have a period very often as well, so that is normal.
Might want to look into another form of BC....have you thought about an IUD? That's what I will be getting after I give birth to my third. I don't want to have to think about it.