I hate to say this, but I would not travel with sick kids. Who feels like traveling when they are sick, what about spreading germs to the other passengers onboard, and also, I was over being sick with a cold, but still had sinus pain and pressure and when we got to the full altitude, it felt like my head was going to implode for the rest of the trip! I was in pure agony and nothing helped! I just sat there, an adult woman, surrounded by all those other people with my head between my hands, trying not to scream in agony. A very kind flight attendant even handed me a styro cup with a napkin she had wet and put in the micro, and I had to hold those cups over my ears, to see if the steam or warmth helped. It relieved it a bit, but not very much. Plus, you can imagine how I felt holding those stupid cups over my ears. I have never flown again right after a cold. It's just not worth it. Kids are always more comfortable at home. I'd keep them there. I hate it when someone comes on a plane and is coughing or sneezing and spreading their germs all over me. You have to think of that, too. It's just NOT right. But, I wish you the best of luck with your miserable little ones. I know it makes you miserable too.