We live on a heavily wooded lot backed up to an 85 acre park (flea and tick infested I am sure!!) Lot of wildlife (which I love) but not including the snakes.
My approach is probably not popular due to it being a chemical that we use in the house. IF you or your family have health issues....it might not be the best route for you. I am just stating what works for us.
Our routine includes a fogger EVERY 3 months or so....depending on the weather. We buy the Raid foggers at Home depot (3/pack and about $12/pack). We use about 9 packs for our home (Large home and yard) each time. We have at least one in every room, garage and attic areas.
We pack up the dogs and rabbit in my old minivan and just go away for 3-4 hours. I pack up picnic lunches, the laptops, phones, radio, ipod, etc. I open ALL cabinets, cover all pillows, etc IT WORKS.
NOW.....BEFORE we do this.....hubby treats our yard and uses a liquid spray around the foundation.
We probably spend upwards of $200 BUT we have no issues with fleas, ticks, or any bugs, lizards, nothing and we live on a heavily wooded lot. This process also keeps away the snakes, lizards etc because they feed on the insects.
Our cue to treat our yard is when we start seeing the copperhead snakes and lizards. It simply depends on the weather and how we approach the best time to treat. The thing to remember is to treat the YARD, FOUNDATION and HOUSE. I have numerous exterminators soliciting me because of where I live and they are shocked when they realize, we have no bugs, fleas, or tick problems.
Good luck!