I did the same type of trip with my daughter when she was 10 months old. After that, we travelled constantly and later with her brother. Most important, careful planning!! Lots of small toys, thin, paper books, empty sippy (for water to drink when taking off and landing, for ear pain), always more diapers than you think (change baby in advance of boarding plane in a nice, large, calm family bathroom-hubby can go in too). This worked for us: take a decent size blanket or one she already uses, if she falls asleep on plane, cover her car seat to block out lights and movements. But best of all, strollers, get a lightweight backpack stroller (InStep Backpack Stroller, discontinued now but some online stores still have and Ebay). This was unbelievably indispensable. Fits in overhead or can gate check. Super light and folded up fast AND fits between plane aisles. Has basket for kids' stuff. And just put baby on back when you need both hands for getting luggage or running through concourses. I was also able to place my carseat on the handles while still being able to push it thru the airport with my kid riding inside! Bring Baby Bjorn also! One thing that we still do, and my kids are now 8 and 5, is bring a backpack that is only for their stuff. Don't mix your diaper bag and/or purse with this backpack. And whenever we needed baby to sit with either mom or dad, backpack went b/w us and we could both grab stuff out... now they carry their own backpacks and love it. So do we! You won't believe how much stuff you'll have to use your hands for (tickets, ID, waters, your own bags)Lots of luck!!! With daughter's backpack and with backpack stroller, you could each put one of these on your backs and both have your hands free to hold each others.. ha!