J.W.
No. The problem is if YOU are RH-negative and the baby is RH-Positive, you can develop antibodies to the baby and attack it. It is worse for the second pregnancy with an RH-positive baby.
O-negative is actually a universal blood donor, with a lack of antigens.
http://www.americanpregnancy.org/pregnancycomplications/r...
There are many other things that can potentially raise risk of miscarriages. The best think is to talk to a fertility specialist.