I have 2 friends that have been diagnosed with Bi-Polar disorder. One takes an MOAI drug and the other takes Lithium. The one on the MAOI is always frantically worried about everything she puts in her mouth. There are so many dreadful interactions to worry about. Even cheese can make her sick. She had a severe headache one time and her friend gave her a OTC pain med. She was on the highway coming through Kansas and they had to stop at an ER just after they crossed the Oklahoma state line. She was put in the hospital.
MAOI drugs are stressful and require a dedicated person to manage their diet and all possible meds. They work wonderfully on the bipolar illness though. The side effects can easily outweigh the illness if it is not manageable with another type of medication.
The one that takes the Lithium has to go to the hospital all the time to get blood drawn for her levels. She has to make herself drink more water and she can't eat much salt. She has dietary issues but not as severe as the other med.
When they are on their meds they are good to go. When they get off their meds they have the issues again. Sad as it is, a medical health diagnosis isn't usually fixable. It's manageable with meds almost all the time though.