We have been considering relocating as well....at least I have!! :) Hubby is a creature of habit!!
Much depends upon what you and/or your husband do for a living. What standard you are used to living now and what you expect. We currently live in Reston, VA - just outside of DC - I love my neighborhood and home. We have a 3sqft, 5bd/3FB 2 car attached garage home...we purchased for 176K now we could probably sell for $550K
We've considered Colorado Springs, CO - although the winters may make it hard on you but the summers are great. The housing market there has not suffered at all and for me to get the same home I have now will cost me more than here.
We've also considered Acworth, GA - I can get a BIGGER HOME on a huge lot for less than $300K...RIGHT NOW - that doesn't mean the market won't change in the future.
I (PERSONALLY) would avoid California like the plague. I'm from there my parents and friends still live there and my parents can't sell their home for what they owe on it. So they are stuck. I have friends in LA and Orange County - while they don't plan on moving anytime soon - they too would be hard pressed to sell and get what they owe on it if they had to sell right now.
Florida is nice - I've never personally been there but my cousin lives in Jacksonville and she LOVES it!! She's originally from Montana. The housing market is depressed there as well - at least it was a few months ago.
Basically, you need to consider if your or your husband's line of work is in the area you want to move to, find out what they are willing to pay there in salary and benefits - those things can make the determining factor for your move.
My husband's job wants us to move to Huntsville, AL - thanks but no thanks. I could get a HUGE home, tennis court, pool and land there for pennies on the dollar. However, my husband would take a cut in pay for the difference in cost of living in AL vs VA. Sorry. I won't do that.