My son went through something very similar, although his period was from about 8 to 11 each night. Lots of crying, just couldn't be soothed. It was hard on him and hard on us, too! But eventually he grew out of it (early in the 3rd month). Our doctor said that it's typical for young babies to have a regular fussy period each night and that if he didn't seem to be in acute pain and it wasn't happening at other times of the day, not to worry.
In the meantime, just keep trying different things to see if they help him to calm down. For us, nothing worked all of the time, but some things that did work included being swaddled, being carried in the Bjorn (facing my chest), using a pacifier, being in the bouncy chair, and listening to music with heavy bass/beat. He also liked taking a bath, though would fuss again when it was over. We also noticed at times that the more things we tried, the more keyed up he would get - maybe we were over-stimulating him. So at times all we did was hold in him the football hold, facing outward, and walk.
The DVD/book "The Happiest Baby on the Block" by Dr. Harvey Karp was helpful to us with some of its suggestions, too.
I know how hard this can be... hang in there, it really does get better!!!